Free Access
Reprod. Nutr. Dev.
Volume 46, Number 5, September-October 2006
5th annual INRA-Meeting: Mammary gland and milk
Page(s) 589 - 598
Published online 23 September 2006
Reprod. Nutr. Dev. 46 (2006) 589-598
DOI: 10.1051/rnd:2006030

Changes in mammary uptake and metabolic fate of glucose with once-daily milking and feed restriction in dairy cows

Jocelyne Guinard-Flament, Eloise Delamaire, Sophie Lemosquet, Marion Boutinaud and Yolande David

UMR INRA/Agrocampus Rennes Production du Lait, 65 rue de St-Brieuc, CS 84215, 35042 Rennes Cedex, France

(Published online 23 September 2006)

Abstract - The aim of this review is to better understand the regulation of milk yield in response to once-daily milking and feed restriction. Glucose is the principal precursor for the synthesis of lactose (a major osmotic agent in milk), and participates in determining the milk volume produced. When applying these two breeding factors, reductions in milk yield are associated with a reduction in milk lactose yield and in the arterial flow of glucose, due to a decrease in the mammary blood flow. The ability of the udder to extract glucose is altered with once-daily milking but not necessarily with feed restriction. Lactose synthesis is down-regulated in response to once-daily milking and feed restriction but the percentage of the extracted glucose which is converted into lactose is differently affected in response to treatments. No marked change is observed with once daily milking whereas this would be increased with feed restriction and in contrast, depressed with fasting.

Key words: milk yield / glucose / mammary gland / uptake / metabolic fate / ruminants

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© INRA, EDP Sciences 2006