Free Access
Reprod. Nutr. Dev.
Volume 43, Number 4, July-August 2003
Page(s) 357 - 370
Reprod. Nutr. Dev. 43 (2003) 357-370
DOI: 10.1051/rnd:2003026

Propionate supplementation did not increase whole body glucose turnover in growing lambs fed rye grass

Linda Majdouba, Michel Beylotb, Michel Vermorela and Isabelle Ortigues-Martya

a  Unité de Recherches sur les Herbivores, INRA Theix, 63122 Saint-Genès-Champanelle, France
b  Unité 499, INSERM, Faculté de Médecine Laennec, rue Gérard Paradin, 69008 Lyon, France

(Received 16 November 2002; accepted 24 June 2003)

The objective of the present study was to investigate the effects of propionate supplementation on whole body glucose turnover in growing lambs fed frozen rye-grass at 1.5  $\times$ maintenance using [ 1- 13C] -glucose. Intraruminal infusion of propionate (0.55 and 0.91 mol $\cdot$d -1) increased the ruminal molar proportions of propionate from 25% with the control to 40% with the highest propionate treatment. It did not however modify glucose turnover (26 mmol $\cdot$d $^{-1}\cdot$kg -1), nor the conversion of its carbon into L-lactate (21%) and alanine (21%), nor glucose recycling (9%). All of the results suggest that in the present conditions glucose turnover and metabolism were not influenced by the supply of propionate.

Key words: glucose turnover / propionate / growing lambs / [ 1- 13C] -glucose

Correspondence and reprints: Isabelle Ortigues-Marty

© INRA, EDP Sciences 2003