Reprod. Nutr. Dev.
Volume 43, Number 4, July-August 2003
|Page(s)||357 - 370|
Propionate supplementation did not increase whole body glucose turnover in growing lambs fed rye grassLinda Majdouba, Michel Beylotb, Michel Vermorela and Isabelle Ortigues-Martya
a Unité de Recherches sur les Herbivores, INRA Theix, 63122 Saint-Genès-Champanelle, France
b Unité 499, INSERM, Faculté de Médecine Laennec, rue Gérard Paradin, 69008 Lyon, France
(Received 16 November 2002; accepted 24 June 2003)
The objective of the present study was to investigate the effects of propionate supplementation on whole body glucose turnover in growing lambs fed frozen rye-grass at 1.5 maintenance using [ 1- 13C] -glucose. Intraruminal infusion of propionate (0.55 and 0.91 mol d -1) increased the ruminal molar proportions of propionate from 25% with the control to 40% with the highest propionate treatment. It did not however modify glucose turnover (26 mmol d kg -1), nor the conversion of its carbon into L-lactate (21%) and alanine (21%), nor glucose recycling (9%). All of the results suggest that in the present conditions glucose turnover and metabolism were not influenced by the supply of propionate.
Key words: glucose turnover / propionate / growing lambs / [ 1- 13C] -glucose
Correspondence and reprints: Isabelle Ortigues-Marty firstname.lastname@example.org
© INRA, EDP Sciences 2003