Propionate supplementation did not increase whole body glucose turnover in growing lambs fed rye grass

Linda Majdoub; Michel Beylot; Michel Vermorel; Isabelle Ortigues-Marty

doi:doi:10.1051/rnd:2003026

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Volume 43 / No 4 (July-August 2003)

Reprod. Nutr. Dev., 43 4 (2003) 357-370

Abstract

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Issue		Reprod. Nutr. Dev. Volume 43, Number 4, July-August 2003


Page(s)		357 - 370
DOI		https://doi.org/10.1051/rnd:2003026

Reprod. Nutr. Dev. 43 (2003) 357-370
DOI: 10.1051/rnd:2003026

Propionate supplementation did not increase whole body glucose turnover in growing lambs fed rye grass

Linda Majdoub^a, Michel Beylot^b, Michel Vermorel^a and Isabelle Ortigues-Marty^a

^a Unité de Recherches sur les Herbivores, INRA Theix, 63122 Saint-Genès-Champanelle, France
^b Unité 499, INSERM, Faculté de Médecine Laennec, rue Gérard Paradin, 69008 Lyon, France

(Received 16 November 2002; accepted 24 June 2003)

Abstract
The objective of the present study was to investigate the effects of propionate supplementation on whole body glucose turnover in growing lambs fed frozen rye-grass at 1.5 $\times$ maintenance using [ 1- ¹³C] -glucose. Intraruminal infusion of propionate (0.55 and 0.91 mol $\cdot$ d ^-1) increased the ruminal molar proportions of propionate from 25% with the control to 40% with the highest propionate treatment. It did not however modify glucose turnover (26 mmol $\cdot$ d $^{-1}\cdot$ kg ^-1), nor the conversion of its carbon into L-lactate (21%) and alanine (21%), nor glucose recycling (9%). All of the results suggest that in the present conditions glucose turnover and metabolism were not influenced by the supply of propionate.

Key words: glucose turnover / propionate / growing lambs / [ 1- ¹³C] -glucose

Correspondence and reprints: Isabelle Ortigues-Marty ortigues@clermont.inra.fr

© INRA, EDP Sciences 2003