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Feeding flaxseed in grass hay and barley silage diets to beef cows increases alpha-linolenic acid and its biohydrogenation intermediates in subcutaneous fat1
Dairy fat blends high in α-linolenic acid are superior to n-3 fatty-acid-enriched palm oil blends for increasing DHA levels in the brains of young rats
Qin Du, Jean-Charles Martin, Genevieve Agnani, Nicole Pages, Pascale Leruyet, Pierre Carayon and Bernadette Delplanque The Journal of Nutritional Biochemistry 23(12) 1573 (2012) https://doi.org/10.1016/j.jnutbio.2011.10.011
α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis
An Pan, Mu Chen, Rajiv Chowdhury, Jason HY Wu, Qi Sun, Hannia Campos, Dariush Mozaffarian and Frank B Hu The American Journal of Clinical Nutrition 96(6) 1262 (2012) https://doi.org/10.3945/ajcn.112.044040
Lipidomics of Alzheimer’s disease: a liver peroxisomal dysfunction in the metabolism of omega-3 fatty acids
Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome—LIPGENE: a European randomized dietary intervention study
Evaluation of breed effects on n-3 PUFA metabolism with dietary flaxseed oil supplementation in dogs
Dharma Purushothaman, Wendy Yvonne Brown, Shu-Biao Wu and Barbara Vanselow British Journal of Nutrition 106(S1) S139 (2011) https://doi.org/10.1017/S0007114511000523
Heritability and mechanisms of n−3 long chain polyunsaturated fatty acid deposition in the flesh of Atlantic salmon
Michael J. Leaver, John B. Taggart, Laure Villeneuve, et al. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 6(1) 62 (2011) https://doi.org/10.1016/j.cbd.2010.04.002
Expanding the docosahexaenoic acid food web for sustainable production: engineering lower plant pathways into higher plants
Chemical Characterization of Sacha Inchi (Plukenetia volubilis L.) Oil
Chiara Fanali, Laura Dugo, Francesco Cacciola, Marco Beccaria, Simone Grasso, Marina Dachà, Paola Dugo and Luigi Mondello Journal of Agricultural and Food Chemistry 59(24) 13043 (2011) https://doi.org/10.1021/jf203184y
Protocol for the Cognitive Interventions and Nutritional Supplements (CINS) trial: A randomized controlled multicenter trial of a brief intervention (BI) versus a BI plus cognitive behavioral treatment (CBT) versus nutritional supplements for patients with long-lasting muscle and back pain
Silje E Reme, Torill H Tveito, Trudie Chalder, Tormod Bjørkkjær, Aage Indahl, Jens I Brox, Egil Fors, Eli M Hagen and Hege R Eriksen BMC Musculoskeletal Disorders 12(1) (2011) https://doi.org/10.1186/1471-2474-12-152
Supplementation with a Fish Oil-Enriched, High-Protein Medical Food Leads to Rapid Incorporation of EPA into White Blood Cells and Modulates Immune Responses within One Week in Healthy Men and Women1,2
Joyce Faber, Marloes Berkhout, Arjan P. Vos, John W.C. Sijben, Philip C. Calder, Johan Garssen and Ardy van Helvoort The Journal of Nutrition 141(5) 964 (2011) https://doi.org/10.3945/jn.110.132985
Balancing the benefits of n-3 polyunsaturated fatty acids and the risks of methylmercury exposure from fish consumption
Increased Δ5- and Δ6-desaturase, cyclooxygenase-2, and lipoxygenase-5 expression and activity are associated with fatty acid and eicosanoid changes in cystic fibrosis
Sarah W. Njoroge, Adam C. Seegmiller, Waddah Katrangi and Michael Laposata Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1811(7-8) 431 (2011) https://doi.org/10.1016/j.bbalip.2011.05.002
Dietary ratio of n-6 to n-3 polyunsaturated fatty acids and periodontal disease in community-based older Japanese: A 3-year follow-up study
High-Dose Docosahexaenoic Acid Supplementation of Preterm Infants: Respiratory and Allergy Outcomes
Brett J. Manley, Maria Makrides, Carmel T. Collins, Andrew J. McPhee, Robert A. Gibson, Philip Ryan, Thomas R. Sullivan and Peter G. Davis Pediatrics 128(1) e71 (2011) https://doi.org/10.1542/peds.2010-2405
Omega-3 fatty acids and metabolic syndrome: Effects and emerging mechanisms of action
Effects of different dietary omega-6/3 polyunsaturated fatty acids ratios on infarct size and the limbic system after myocardial infarction
I. Rondeau, S. Picard, T. M. Bah, et al. Canadian Journal of Physiology and Pharmacology 89(3) 169 (2011) https://doi.org/10.1139/Y11-007
Marine Medicinal Foods - Implications and Applications, Macro and Microalgae
Ladislava Mišurcová, Jarmila Ambrožová and Dušan Samek Advances in Food and Nutrition Research, Marine Medicinal Foods - Implications and Applications, Macro and Microalgae 64 339 (2011) https://doi.org/10.1016/B978-0-12-387669-0.00027-2
Docosapentaenoic acid (22:5n-3): A review of its biological effects
Fatty acid desaturase 2 promoter mutation is not responsible for Δ6-desaturase deficiency
Melissa K Gregory, Susan E Lester, Rebecca J Cook-Johnson, et al. European Journal of Human Genetics 19(11) 1202 (2011) https://doi.org/10.1038/ejhg.2011.104
Dietary Flavonoids Increase Plasma Very Long-Chain (n-3) Fatty Acids in Rats,
Marie-Claire Toufektsian, Patricia Salen, Franois Laporte, Chiara Tonelli and Michel de Lorgeril The Journal of Nutrition 141(1) 37 (2011) https://doi.org/10.3945/jn.110.127225
Delta-8 desaturation activity varies among fatty acyl desaturases of teleost fish: High activity in delta-6 desaturases of marine species
Óscar Monroig, Yuanyou Li and Douglas R. Tocher Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 159(4) 206 (2011) https://doi.org/10.1016/j.cbpb.2011.04.007
RETRACTED: Liver conversion of docosahexaenoic and arachidonic acids from their 18-carbon precursors in rats on a DHA-free but α-LNA-containing n−3 PUFA adequate diet
Fei Gao, Hyung-Wook Kim, Miki Igarashi, et al. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1811(7-8) 484 (2011) https://doi.org/10.1016/j.bbalip.2011.05.008
Towards a whole-body systems [multi-organ] lipidomics in Alzheimer’s disease
Brain histological changes in young mice submitted to diets with different ratios of n-6/n-3 polyunsaturated fatty acids during maternal pregnancy and lactation
HIgh dietary and plasma levels of the omega-3 fatty acid docosahexaenoic acid are associated with decreased dementia risk: the rancho bernardo study
L.B. Lopez, Donna Kritz-Silverstein and Elizabeth Barrett-Connor The Journal of nutrition, health and aging 15(1) 25 (2011) https://doi.org/10.1007/s12603-011-0009-5
Protective effects of prescription n-3 fatty acids against impairment of spatial cognitive learning ability in amyloid β-infused rats
High content of long-chain n-3 polyunsaturated fatty acids in red blood cells of Kenyan Maasai despite low dietary intake
Nadja Knoll, Katrin Kuhnt, Florence M Kyallo, Beatrice N Kiage-Mokua and Gerhard Jahreis Lipids in Health and Disease 10(1) (2011) https://doi.org/10.1186/1476-511X-10-141
Nutritional Deficiencies and Phospholipid Metabolism
María S. Gimenez, Liliana B. Oliveros and Nidia N. Gomez International Journal of Molecular Sciences 12(4) 2408 (2011) https://doi.org/10.3390/ijms12042408
Effects of Flaxseed Lignan and Oil on Bone Health of Breast-Tumor-Bearing Mice Treated With or Without Tamoxifen
Jianmin Chen, Jasdeep K. Saggar, Wendy E. Ward and Lilian U. Thompson Journal of Toxicology and Environmental Health, Part A 74(12) 757 (2011) https://doi.org/10.1080/15287394.2011.567950
Fatty acid composition of beef from Nguni steers supplemented with Acacia karroo leaf-meal
The relation between the omega-3 index and arachidonic acid is bell shaped: Synergistic at low EPA+DHA status and antagonistic at high EPA+DHA status
Martine F. Luxwolda, Remko S. Kuipers, Ella N. Smit, et al. Prostaglandins, Leukotrienes and Essential Fatty Acids 85(3-4) 171 (2011) https://doi.org/10.1016/j.plefa.2011.05.004
Efficient Synthesis of the Very‐Long‐Chain n‐3 Fatty Acids, Tetracosahexaenoic Acid (C24:6n‐3) and Tricosahexaenoic Acid (C23:6n‐3)
Dietary intake and status of n–3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the precursor-product ratio of α-linolenic acid to long-chain n–3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort
Ailsa A Welch, Subodha Shakya-Shrestha, Marleen AH Lentjes, Nicholas J Wareham and Kay-Tee Khaw The American Journal of Clinical Nutrition 92(5) 1040 (2010) https://doi.org/10.3945/ajcn.2010.29457
High dietary and plasma levels of the omega-3 fatty acid docosahexaenoic acid are associated with decreased dementia risk: The Rancho Bernardo study
Gender affects liver desaturase expression in a rat model of n−3 fatty acid repletion
Audrey Extier, Bénédicte Langelier, Marie-Hélène Perruchot, Philippe Guesnet, Paul P. Van Veldhoven, Monique Lavialle and Jean-Marc Alessandri The Journal of Nutritional Biochemistry 21(3) 180 (2010) https://doi.org/10.1016/j.jnutbio.2008.10.008
Dietary fish oil n-3 polyunsaturated fatty acids and alpha-linolenic acid differently affect brain accretion of docosahexaenoic acid and expression of desaturases and sterol regulatory element-binding protein 1 in mice
Effects of Docosahexaenoic Acid Supplementation During Pregnancy on Gestational Age and Size at Birth: Randomized, Double-Blind, Placebo-Controlled Trial in Mexico
Usha Ramakrishnan, Aryeh D. Stein, Socorro Parra-Cabrera, Meng Wang, Beth Imhoff-Kunsch, Sergio Juárez-Márquez, Juan Rivera and Reynaldo Martorell Food and Nutrition Bulletin 31(2_suppl2) S108 (2010) https://doi.org/10.1177/15648265100312S203
An α-Linolenic Acid-Rich Formula Reduces Oxidative Stress and Inflammation by Regulating NF-κB in Rats with TNBS-Induced Colitis ,
Aktham Hassan, Ayman Ibrahim, Khaly Mbodji, Moïse Coëffier, Frédéric Ziegler, Frédéric Bounoure, Jean-Michel Chardigny, Mohamed Skiba, Guillaume Savoye, Pierre Déchelotte and Rachel Marion-Letellier The Journal of Nutrition 140(10) 1714 (2010) https://doi.org/10.3945/jn.109.119768
Composition en acides gras des œufs. Intérêt nutritionnel et valeur santé
Significance of long-chain polyunsaturated fatty acids (PUFAs) for the development and behaviour of children
Jan Philipp Schuchardt, Michael Huss, Manuela Stauss-Grabo and Andreas Hahn European Journal of Pediatrics 169(2) 149 (2010) https://doi.org/10.1007/s00431-009-1035-8
Every egg may have a targeted purpose: toward a differential approach to egg according to composition and functional effect
Dietary Milled Flaxseed and Flaxseed Oil Improve N-3 Fatty Acid Status and Do Not Affect Glycemic Control in Individuals with Well-Controlled Type 2 Diabetes
Carla G Taylor, Amy D Noto, Danielle M Stringer, Sylvia Froese and Linda Malcolmson Journal of the American College of Nutrition 29(1) 72 (2010) https://doi.org/10.1080/07315724.2010.10719819
Postgraduate Symposium Long-chain n-3 PUFA: intakes in the UK and the potential of a chicken meat prototype to increase them
Environmental contaminants and human health in the Canadian Arctic
S.G. Donaldson, J. Van Oostdam, C. Tikhonov, M. Feeley, B. Armstrong, P. Ayotte, O. Boucher, W. Bowers, L. Chan, F. Dallaire, R. Dallaire, É. Dewailly, J. Edwards, G.M. Egeland, J. Fontaine, C. Furgal, T. Leech, E. Loring, G. Muckle, T. Nancarrow, D. Pereg, P. Plusquellec, M. Potyrala, O. Receveur and R.G. Shearer Science of The Total Environment 408(22) 5165 (2010) https://doi.org/10.1016/j.scitotenv.2010.04.059
Effects of diet, age and gender on the polyunsaturated fatty acid composition of broiler anatomical compartments
Gender-specific fatty acid profiles in platelet phosphatidyl-choline and -ethanolamine
J. Geppert, Y. Min, M. Neville, C. Lowy and K. Ghebremeskel Prostaglandins, Leukotrienes and Essential Fatty Acids 82(1) 51 (2010) https://doi.org/10.1016/j.plefa.2009.09.002
Multiple genes for functional ∆6 fatty acyl desaturases (Fad) in Atlantic salmon (Salmo salar L.): Gene and cDNA characterization, functional expression, tissue distribution and nutritional regulation
Óscar Monroig, Xiaozhong Zheng, Sofia Morais, et al. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1801(9) 1072 (2010) https://doi.org/10.1016/j.bbalip.2010.04.007
Effect of Omega-3 Fish Oil on Cardiovascular Risk in Diabetes
Dietary intake of stearidonic acid–enriched soybean oil increases the omega-3 index: randomized, double-blind clinical study of efficacy and safety
Shawna L Lemke, John L Vicini, Hong Su, Daniel A Goldstein, Margaret A Nemeth, Elaine S Krul and William S Harris The American Journal of Clinical Nutrition 92(4) 766 (2010) https://doi.org/10.3945/ajcn.2009.29072
Differential effects of steroids on the synthesis of polyunsaturated fatty acids by human neuroblastoma cells
Long-chain polyunsaturated fatty acid synthesis in fish: Comparative analysis of Atlantic salmon (Salmo salar L.) and Atlantic cod (Gadus morhua L.) Δ6 fatty acyl desaturase gene promoters
Xiaozhong Zheng, Michael J. Leaver and Douglas R. Tocher Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 154(3) 255 (2009) https://doi.org/10.1016/j.cbpb.2009.06.010
α-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans
J. Thomas Brenna, Norman Salem, Andrew J. Sinclair and Stephen C. Cunnane Prostaglandins, Leukotrienes and Essential Fatty Acids 80(2-3) 85 (2009) https://doi.org/10.1016/j.plefa.2009.01.004
Direct Diet Quantification Indicates Low Intakes of (n-3) Fatty Acids in Children 4 to 8 Years Old
Whole-body synthesis secretion of docosahexaenoic acid from circulating eicosapentaenoic acid in unanesthetized rats
Fei Gao, Dale Kiesewetter, Lisa Chang, Kaizong Ma, Stanley I. Rapoport and Miki Igarashi Journal of Lipid Research 50(12) 2463 (2009) https://doi.org/10.1194/jlr.M900223-JLR200
Dietary perilla oil lowers serum lipids and ovalbumin-specific IgG1, but increases total IgE levels in ovalbumin-challenged mice
n-3 PUFA Fortification of High n-6 PUFA Farmed Tilapia with Linseed Could Significantly Increase Dietary Contribution and Support Nutritional Expectations of Fish
Niva Shapira, Pierre Weill, Ossie Sharon, Rachel Loewenbach and Ofer Berzak Journal of Agricultural and Food Chemistry 57(6) 2249 (2009) https://doi.org/10.1021/jf8029258
Is there a dietary requirement for DHA in pregnancy?
Does dietary DHA improve neural function in children? Observations in phenylketonuria
Berthold Koletzko, Skadi Beblo, Hans Demmelmair, Wolfgang Müller-Felber and Fabienne L. Hanebutt Prostaglandins, Leukotrienes and Essential Fatty Acids 81(2-3) 159 (2009) https://doi.org/10.1016/j.plefa.2009.06.006
Whole-body synthesis-secretion rates of long-chain n-3 PUFAs from circulating unesterified α-linolenic acid in unanesthetized rats
Fei Gao, Dale Kiesewetter, Lisa Chang, Kaizong Ma, Jane M. Bell, Stanley I. Rapoport and Miki Igarashi Journal of Lipid Research 50(4) 749 (2009) https://doi.org/10.1194/jlr.D800056-JLR200
Supercritical CO2 extraction of omega-3 rich oil from Sacha inchi (Plukenetia volubilis L.) seeds
Luis A. Follegatti-Romero, Carla R. Piantino, Renato Grimaldi and Fernando A. Cabral The Journal of Supercritical Fluids 49(3) 323 (2009) https://doi.org/10.1016/j.supflu.2009.03.010