Free Access
| Issue |
Reprod. Nutr. Dev.
Volume 45, Number 3, May-June 2005
SYMPOSIUM: Homage to Professor Charles Thibault
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| Page(s) | 255 - 259 | |
| DOI | https://doi.org/10.1051/rnd:2005018 | |
Reprod. Nutr. Dev. 45 (2005) 255-259
DOI: 10.1051/rnd:2005018
Unité de Physiologie de la Reproduction et des Comportements, Institut National de la Recherche Agronomique (INRA), Centre National de la Recherche Scientifique (CNRS) et Université François Rabelais de Tours, 37 380 Nouzilly, France
Key words: half-life / gonadotropin / carbohydrate / recombinant hormone / baculovirus
Corresponding author: Yves Combarnous ombarno@tours.inra.fr
© INRA, EDP Sciences 2005
DOI: 10.1051/rnd:2005018
Involvement of equine chorionic gonadotropin (eCG) carbohydrate side chains in its bioactivity; lessons from recombinant hormone expressed in insect cells
Sébastien Legardinier, Claire Cahoreau, Danièle Klett and Yves CombarnousUnité de Physiologie de la Reproduction et des Comportements, Institut National de la Recherche Agronomique (INRA), Centre National de la Recherche Scientifique (CNRS) et Université François Rabelais de Tours, 37 380 Nouzilly, France
Abstract - Natural eCG consists of as much as 45% carbohydrate side chains. The present paper deals with the analysis of the roles of the N- and O-linked saccharides of this hormone in the different steps of its activity and its possible repacement by recombinant eCG expressed in baculovirus - insect cell systems.
Key words: half-life / gonadotropin / carbohydrate / recombinant hormone / baculovirus
Corresponding author: Yves Combarnous ombarno@tours.inra.fr
© INRA, EDP Sciences 2005