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Neuroprotective Role of Omega-3 Fatty Acids: Fighting Alzheimer’s Disease
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Strategic delivery of omega-3 fatty acids for modulating inflammatory neurodegenerative diseases
Long-Term Fish Oil Supplementation Attenuates Spike Wave Discharges in the Amygdala of Adult Rats with Early-Life Febrile Seizures
Leopoldo Eduardo Flores-Mancilla, Marisela Hernández-González, Miguel Ángel Guevara-Pérez, Herlinda Bonilla-Jaime, Noemí Gaytán-Pacheco, Claudia Araceli Reyes-Estrada and Fermín Paul Pacheco-Moisés Brain Sciences 15(4) 395 (2025) https://doi.org/10.3390/brainsci15040395
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Human FABP7 selectively captures docosahexaenoic acid over eicosapentaenoic acid: A potential protein-based platform for affinity purification of ω-3 lipids
Network Meta-Analysis Indicates Superior Effects of Omega-3 Polyunsaturated Fatty Acids in Preventing the Transition to Psychosis in Individuals at Clinical High-Risk
Chengfeng Chen, Yongyan Deng, Yuling Li, Meiting Zhang, Tong Yu, Kun Xie, Wuyou Bao, Peiying Li, Ling Sun, Tianhong Zhang, Yikang Zhu and Bin Zhang International Journal of Neuropsychopharmacology 27(3) (2024) https://doi.org/10.1093/ijnp/pyae014
Untargeted metabolomics reveals that declined PE and PC in obesity may be associated with prostate hyperplasia
Guorui Fan, Xiaohai Guan, Bo Guan, Hongfei Zhu, Yongchao Pei, Chonghao Jiang, Yonggui Xiao, Zhiguo Li, Fenghong Cao and Stanisław Jacek Wroński PLOS ONE 19(4) e0301011 (2024) https://doi.org/10.1371/journal.pone.0301011
Effects of Omega-3 Polyunsaturated Fatty Acids, Docosahexaenoic Acid and Eicosapentaenoic Acid, on Post-Surgical Complications in Surgical Trauma Patients: Mechanisms, Nutrition, and Challenges
Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling
Marie-Lise Jobin, Véronique De Smedt-Peyrusse, Fabien Ducrocq, Rim Baccouch, Asma Oummadi, Maria Hauge Pedersen, Brian Medel-Lacruz, Maria-Florencia Angelo, Sandrine Villette, Pierre Van Delft, Laetitia Fouillen, Sébastien Mongrand, Jana Selent, Tarson Tolentino-Cortez, Gabriel Barreda-Gómez, Stéphane Grégoire, Elodie Masson, Thierry Durroux, Jonathan A. Javitch, Ramon Guixà-González, Isabel D. Alves and Pierre Trifilieff Molecular Psychiatry 28(5) 1960 (2023) https://doi.org/10.1038/s41380-022-01928-6
Interdisciplinary Approaches to Deal with Alzheimer’s Disease—From Bench to Bedside: What Feasible Options Do Already Exist Today?
Irene Ablinger, Katharina Dressel, Thea Rott, Anna Andrea Lauer, Michael Tiemann, João Pedro Batista, Tim Taddey, Heike Sabine Grimm and Marcus Otto Walter Grimm Biomedicines 10(11) 2922 (2022) https://doi.org/10.3390/biomedicines10112922
Docosahexaenoic acid enrichment of tumor phospholipid membranes increases tumor necroptosis in mice bearing triple negative breast cancer patient-derived xenografts
Marnie Newell, Susan Goruk, Julia Schueler, Vera Mazurak, Lynne-Marie Postovit and Catherine J Field The Journal of Nutritional Biochemistry 107 109018 (2022) https://doi.org/10.1016/j.jnutbio.2022.109018
Glucosinolates and Omega-3 Fatty Acids from Mustard Seeds: Phytochemistry and Pharmacology
Gitishree Das, Ourlad Alzeus G. Tantengco, Rosa Tundis, Joyce Ann H. Robles, Monica Rosa Loizzo, Han Seung Shin and Jayanta Kumar Patra Plants 11(17) 2290 (2022) https://doi.org/10.3390/plants11172290
The lipid environment modulates cardiolipin and phospholipid constitution in wild type and tafazzin‐deficient cells
Gregor Oemer, Jakob Koch, Yvonne Wohlfarter, Katharina Lackner, Rita E. M. Gebert, Stephan Geley, Johannes Zschocke and Markus A. Keller Journal of Inherited Metabolic Disease 45(1) 38 (2022) https://doi.org/10.1002/jimd.12433
Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis
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The Relationship between Fatty Acids and the Development, Course and Treatment of Rheumatoid Arthritis
Wojciech Tański, Natalia Świątoniowska-Lonc, Mateusz Tabin and Beata Jankowska-Polańska Nutrients 14(5) 1030 (2022) https://doi.org/10.3390/nu14051030
Lipid Dys-Homeostasis Contributes to APOE4-Associated AD Pathology
Adina-Nicoleta Lazar, Linda Hanbouch, Lydie Boussicaut, Baptiste Fourmaux, Patricia Daira, Mark J. Millan, Nathalie Bernoud-Hubac and Marie-Claude Potier Cells 11(22) 3616 (2022) https://doi.org/10.3390/cells11223616
Marie-Lise Jobin, Véronique De Smedt-Peyrusse, Fabien Ducrocq, Asma Oummadi, Rim Baccouch, Maria Hauge Pedersen, Brian Medel-Lacruz, Pierre Van Delft, Laetitia Fouillen, Sébastien Mongrand, Jana Selent, Tarson Tolentino-Cortez, Gabriel Barreda-Gómez, Stéphane Grégoire, Elodie Masson, Thierry Durroux, Jonathan A. Javitch, Ramon Guixà-González, Isabel D. Alves and Pierre Trifilieff (2022) https://doi.org/10.1101/2022.01.04.474945
Ram B. Singh, Rie Horiuchi, Agnieszka Wilczynska, Sonia Suchday, Garima Tyagi, Aminat Magomedova, Ghizal Fatima, Manal M.A. Smail, Adrian Isaza, Monica Jain, Fabien De Meester, Toru Takahashi, Shaw Watanabe, Teiji Nakamura and Lekh Raj Juneja 551 (2022) https://doi.org/10.1016/B978-0-12-819815-5.00030-6
How to boost the effects of exercise to favor traumatic brain injury outcome
Order vs. Disorder: Cholesterol and Omega-3 Phospholipids Determine Biomembrane Organization
Augusta de Santis, Ernesto Scoppola, Maria Francesca Ottaviani, Alexandros Koutsioubas, Lester C. Barnsley, Luigi Paduano, Gerardino D’Errico and Irene Russo Krauss International Journal of Molecular Sciences 23(10) 5322 (2022) https://doi.org/10.3390/ijms23105322
Supervised Machine Learning Models and Protein-Protein Interaction
Network Analysis of Gene Expression Profiles Induced by Omega-3 Polyunsaturated
Fatty Acids
Docosahexaenoic fatty acid reduces the pro‐inflammatory response induced by IL-1β in astrocytes through inhibition of NF-κB and AP-1 transcription factor activation
A Systematic Review of Effectiveness of Omega-3 Fatty Acid Supplementation on Symptoms, Social Functions, and Neurobiological Variables in Schizophrenia
Docosahexaenoic Acid Incorporation Is Not Affected by Doxorubicin Chemotherapy in either Whole Cell or Lipid Raft Phospholipids of Breast Cancer Cells in vitro and Tumor Phospholipids in vivo
Effects of controlled cortical impact and docosahexaenoic acid on rat pup fatty acid profiles
Michelle E. Schober, Daniela F. Requena, J. Alan Maschek, James Cox, Leonardo Parra and Alyssa Lolofie Behavioural Brain Research 378 112295 (2020) https://doi.org/10.1016/j.bbr.2019.112295
Not just a fluidifying effect: omega-3 phospholipids induce formation of non-lamellar structures in biomembranes
Comparative studies of DHA-enriched phosphatidylcholine and recombination of DHA-ethyl ester with egg phosphatidylcholine on ameliorating memory and cognitive deficiency in SAMP8 mice
Some biochemical studies on trans fatty acid-containing diet
Yasmin Ali Abd El-Aal, Doaa Mohamed Abdel-Fattah and Khalifa El-Dawy Ahmed Diabetes & Metabolic Syndrome: Clinical Research & Reviews 13(3) 1753 (2019) https://doi.org/10.1016/j.dsx.2019.03.029
Omega‐3 fatty acids regulate plasticity in distinct hippocampal glutamatergic synapses
Sanjay Aryal, Suleman Hussain, Christian A. Drevon, Erlend Nagelhus, Øyvind Hvalby, Vidar Jensen, Sven Ivar Walaas and Svend Davanger European Journal of Neuroscience 49(1) 40 (2019) https://doi.org/10.1111/ejn.14224
Docosahexaenoic acid, 22:6n‐3: Its roles in the structure and function of the brain
DHA supplementation during prenatal ethanol exposure alters the expression of fetal rat liver genes involved in oxidative stress regulation
Bradley A. Feltham, Xavier L. Louis, Fatemeh Ramezani Kapourchali, Michael N.A. Eskin and Miyoung Suh Applied Physiology, Nutrition, and Metabolism 44(7) 744 (2019) https://doi.org/10.1139/apnm-2018-0580
Maternal Omega-3 Nutrition, Placental Transfer and Fetal Brain Development in Gestational Diabetes and Preeclampsia
Prasad P. Devarshi, Ryan W. Grant, Chioma J. Ikonte and Susan Hazels Mitmesser Nutrients 11(5) 1107 (2019) https://doi.org/10.3390/nu11051107
Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation
Two clusters of residues contribute to the activity and substrate specificity of Fm1, a bifunctional oleate and linoleate desaturase of fungal origin
Yuanheng Cai, Xiao-Hong Yu, Qun Liu, Chang-Jun Liu and John Shanklin Journal of Biological Chemistry 293(51) 19844 (2018) https://doi.org/10.1074/jbc.RA118.005972
Role of the cell membrane interface in modulating production and uptake of Alzheimer's beta amyloid protein
Prashant Bharadwaj, Tanya Solomon, Chris J. Malajczuk, Ricardo L. Mancera, Mark Howard, Damien W.M. Arrigan, Philip Newsholme and Ralph N. Martins Biochimica et Biophysica Acta (BBA) - Biomembranes 1860(9) 1639 (2018) https://doi.org/10.1016/j.bbamem.2018.03.015
The effects of dietary polyunsaturated fatty acids on miR-126 promoter DNA methylation status and VEGF protein expression in the colorectal cancer cells
Mechanisms underlying the effects of n-3 polyunsaturated fatty acids on fear memory processing and their hypothetical effects on fear of cancer recurrence in cancer survivors
Critical effects of polar fluorescent probes on the interaction of DHA with POPC supported lipid bilayers
Kiera R. Flynn, Alessandra Sutti, Lisandra L. Martin, M. Leigh Ackland and Angel A.J. Torriero Biochimica et Biophysica Acta (BBA) - Biomembranes 1860(5) 1135 (2018) https://doi.org/10.1016/j.bbamem.2018.01.013
Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprint
Blake R. Hopiavuori, Martin-Paul Agbaga, Richard S. Brush, Michael T. Sullivan, William E. Sonntag and Robert E. Anderson Journal of Lipid Research 58(4) 668 (2017) https://doi.org/10.1194/jlr.M070714
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders
A Critical Review on the Effect of Docosahexaenoic Acid (DHA) on Cancer Cell Cycle Progression
Marnie Newell, Kristi Baker, Lynne Postovit and Catherine Field International Journal of Molecular Sciences 18(8) 1784 (2017) https://doi.org/10.3390/ijms18081784
Modulation of Ras/ERK and Phosphoinositide Signaling by Long-Chain n-3 PUFA in Breast Cancer and Their Potential Complementary Role in Combination with Targeted Drugs
Nutrition and AGE‐ing: Focusing on Alzheimer’s Disease
Giulia Abate, Mariagrazia Marziano, Wiramon Rungratanawanich, Maurizio Memo, Daniela Uberti and Musthafa Mohamed Essa Oxidative Medicine and Cellular Longevity 2017(1) (2017) https://doi.org/10.1155/2017/7039816
Polyunsaturated fatty acids and suicide risk in mood disorders: A systematic review
Maurizio Pompili, Lucia Longo, Giovanni Dominici, et al. Progress in Neuro-Psychopharmacology and Biological Psychiatry 74 43 (2017) https://doi.org/10.1016/j.pnpbp.2016.11.007
Determination of the Relative Efficacy of Eicosapentaenoic Acid and Docosahexaenoic Acid for Anti-Cancer Effects in Human Breast Cancer Models
Laura VanderSluis, Vera Mazurak, Sambasivarao Damaraju and Catherine Field International Journal of Molecular Sciences 18(12) 2607 (2017) https://doi.org/10.3390/ijms18122607
Polyunsaturated chains in asymmetric lipids disorder raft mixtures and preferentially associate with α-Synuclein
Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells
Feven Tigistu-Sahle, Milla Lampinen, Lotta Kilpinen, Minna Holopainen, Petri Lehenkari, Saara Laitinen and Reijo Käkelä Journal of Lipid Research 58(1) 92 (2017) https://doi.org/10.1194/jlr.M070680
Omega-3 polyunsaturated fatty acids improve the antioxidative defense in rat astrocytes via an Nrf2-dependent mechanism
Folate and long-chain polyunsaturated fatty acid supplementation during pregnancy has long-term effects on the attention system of 8.5-y-old offspring: a randomized controlled trial
Andrés Catena, J Angela Muñoz-Machicao, Francisco J Torres-Espínola, Cristina Martínez-Zaldívar, Carolina Diaz-Piedra, Angel Gil, Gudrun Haile, Eszter Györei, Anne M Molloy, Tamás Decsi, Berthold Koletzko and Cristina Campoy The American Journal of Clinical Nutrition 103(1) 115 (2016) https://doi.org/10.3945/ajcn.115.109108
Docosahexaenoic acid suppresses breast cancer cell metastasis by targeting matrix-metalloproteinases