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Melatonin receptor ligands: A pharmaco‐chemical perspective
Jean A. Boutin, Paula A. Witt‐Enderby, Christoph Sotriffer and Darius P. Zlotos Journal of Pineal Research 69(3) (2020) https://doi.org/10.1111/jpi.12672
Expression of Melatonin and Dopamine D3 Receptor Heteromers in Eye Ciliary Body Epithelial Cells and Negative Correlation with Ocular Hypertension
Irene Reyes-Resina, Hanan Awad Alkozi, Anna del Ser-Badia, Juan Sánchez-Naves, Jaume Lillo, Jasmina Jiménez, Jesús Pintor, Gemma Navarro and Rafael Franco Cells 9(1) 152 (2020) https://doi.org/10.3390/cells9010152
Melatonin modulates proliferation of pancreatic stellate cells through caspase-3 activation and changes in cyclin A and D expression
Melatonin MT1 and MT2 receptor ERK signaling is differentially dependent on Gi/o and Gq/11 proteins
Min Chen, Erika Cecon, Angeliki Karamitri, Wenwen Gao, Romain Gerbier, Raise Ahmad and Ralf Jockers Journal of Pineal Research 68(4) (2020) https://doi.org/10.1111/jpi.12641
Fluorine substituted methoxyphenylalkyl amides as potent melatonin receptor agonists
Ralf Jockers, Philippe Delagrange, Margarita L. Dubocovich, Regina P. Markus, Nicolas Renault, Gianluca Tosini, Erika Cecon and Darius P. Zlotos British Journal of Pharmacology 173(18) 2702 (2016) https://doi.org/10.1111/bph.13536
MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective
Jiabei Liu, Shannon J. Clough, Anthony J. Hutchinson, Ekue B. Adamah-Biassi, Marina Popovska-Gorevski and Margarita L. Dubocovich Annual Review of Pharmacology and Toxicology 56(1) 361 (2016) https://doi.org/10.1146/annurev-pharmtox-010814-124742
Understanding melatonin receptor pharmacology: Latest insights from mouse models, and their relevance to human disease
The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors
Stephen P.H. Alexander, Helen E. Benson, Elena Faccenda, Adam J. Pawson, Joanna L. Sharman, Michael Spedding, John A. Peters and Anthony J. Harmar British Journal of Pharmacology 170(8) 1459 (2013) https://doi.org/10.1111/bph.12445
Design of Novel Melatonin Analogs for the Reduction of Intraocular Pressure in Normotensive Rabbits
Pilar Alarma-Estrany, Ana Guzman-Aranguez, Fernando Huete, Assumpta Peral, Robert Plourde, Teresa Pelaez, Benjamin Yerxa and Jesús Pintor The Journal of Pharmacology and Experimental Therapeutics 337(3) 703 (2011) https://doi.org/10.1124/jpet.110.178319
International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors
Margarita L. Dubocovich, Philippe Delagrange, Diana N. Krause, David Sugden, Daniel P. Cardinali and James Olcese Pharmacological Reviews 62(3) 343 (2010) https://doi.org/10.1124/pr.110.002832
Mapping the Melatonin Receptor. 7. Subtype Selective Ligands Based on β-Substituted N-Acyl-5-methoxytryptamines and β-Substituted N-Acyl-5-methoxy-1-methyltryptamines
Andrew Tsotinis, Margarita Vlachou, Demetris P. Papahatjis, Theodora Calogeropoulou, Spyros P. Nikas, Peter J. Garratt, Vincent Piccio, Stefan Vonhoff, Kathryn Davidson, Muy-Teck Teh and David Sugden Journal of Medicinal Chemistry 49(12) 3509 (2006) https://doi.org/10.1021/jm0512544
Modulation by melatonin of glutamatergic synaptic transmission in the carp retina
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity
Valeria Lucini, Marilou Pannacci, Francesco Scaglione, Franco Fraschini, Sivia Rivara, Marco Mor, Fabrizio Bordi, Pier Vincenzo Plazzi, Gilberto Spadoni, Annalida Bedini, Giovanni Piersanti, Giuseppe Diamantini and Giorgio Tarzia Journal of Medicinal Chemistry 47(17) 4202 (2004) https://doi.org/10.1021/jm040768k
Developments in Tryptophan and Serotonin Metabolism
Gilberto Spadoni, Annalida Bedini, Giovanni Piersanti, et al. Advances in Experimental Medicine and Biology, Developments in Tryptophan and Serotonin Metabolism 527 577 (2003) https://doi.org/10.1007/978-1-4615-0135-0_66
Design and Synthesis of Naphthalenic Dimers as Selective MT1 Melatoninergic Ligands
Carole Descamps-François, Saïd Yous, Philippe Chavatte, Valérie Audinot, Anne Bonnaud, Jean A. Boutin, Philippe Delagrange, Caroline Bennejean, Pierre Renard and Daniel Lesieur Journal of Medicinal Chemistry 46(7) 1127 (2003) https://doi.org/10.1021/jm0255872
Melatonin receptors and their regulation: biochemical and structural mechanisms
Desensitization of pigment granule aggregation in Xenopus leavis melanophores: melatonin degradation rather than receptor down‐regulation is responsible
Serine Residues 110 and 114 Are Required for Agonist Binding but Not Antagonist Binding to the Melatonin MT1 Receptor
Shaun Conway, Elaine S. Mowat, Janice E. Drew, et al. Biochemical and Biophysical Research Communications 282(5) 1229 (2001) https://doi.org/10.1006/bbrc.2001.4722
Melatonin Receptor Signaling: Finding the Path Through the Dark
Activation of MT2 melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock
Amanda E. Hunt, Walid M. Al-Ghoul, Martha U. Gillette and Margarita L. Dubocovich American Journal of Physiology-Cell Physiology 280(1) C110 (2001) https://doi.org/10.1152/ajpcell.2001.280.1.C110
2-N-Acylaminoalkylindoles: Design and Quantitative Structure−Activity Relationship Studies Leading to MT2-Selective Melatonin Antagonists
Gilberto Spadoni, Cesarino Balsamini, Giuseppe Diamantini, Andrea Tontini, Giorgio Tarzia, Marco Mor, Silvia Rivara, Pier Vincenzo Plazzi, Romolo Nonno, Valeria Lucini, Marilou Pannacci, Franco Fraschini and Bojidar Michaylov Stankov Journal of Medicinal Chemistry 44(18) 2900 (2001) https://doi.org/10.1021/jm001125h